Division of Nephrology
Barasch Lab
Overview
The Barasch Lab focuses on the mechanisms of kidney growth and kidney damage. Dr. Barasch’s work began with the identification of a method to generate fully segmented nephrons from renal progenitors (Cell, 1999) and because of this assay, Dr. Barasch has recently defined a novel and critical transcription factor in nephrogenesis and nephron patterning, a Cp2 like factor (JCI, 2014). During this search for growth factors he fourtuitously purified NGAL (Mol Cell, 2002); its expression demonstrated that the first response of the kidney to acute injury was production of an iron chelator for bacteriostasis (Nature Medicine, 2011) by a cell type (interacalated cells) that was not previously thought to play a role in acute kidney injury pathophysiology (JCI 2014). The work not only opened many doors for further inquiry in the response of the kidney to injury, but as a sequel, Barasch introduced the first biomarker of kidney damage to be used clinically (in Europe, Asia; JCI, 2005; Lancet, 2005; Annals of Internal Medicine, 2008; JACC, 2012). Dr. Barasch has been funded continuously by the NIH for the past two decades and is currently funded by two NIH RO1 grants and the March of Dimes. He is also co-Principal Investigator of an NIDDK-sponsored George O’Brien Urology Center (Multi-PI with Drs. Mendelsohn and Gharavi) studying the loss of urinary defense mechanisms as a result of genetic defects in urinary tract formation. He has been a member of the March of Dimes Study Section for 10 years and an ad-hoc reviewer at the NIH and Columbia’s CTSA. Dr. Barasch has hosted more than 30 college and medical, graduate and post-doctoral students in his lab; 7 are now independent scientists, 3 currently hold NIH funding. He also has a leadership role in developing educational programs and career tracks for aspiring clinician scientists. He is the Director of the PhD to MD program, Course Director of Molecular Mechanisms, and Director of the Clinician Scientist Track of House Staff Training in Internal Medicine. Dr. Barasch has received the Bomfalk and the Presidential Awards of Columbia University and recently the Provost Award in novel educational techniques.
Publications
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See a complete list of publications in Pubmed.
Scientists: Current &former
Debanjana Chatterjee, PhD
(Took a job as Clinical Research Manager at Multiple Myeloma Research Foundation )
Jason Zheng
(clinical research coordinator, left to attend medical school)
Byum Hee Kil
( clinical research coordinator, left to attend dental school)
Elisa Delbarba, MD
( postdoctoral fellow, left to work as nephrologist at the Spedali Civili of Brescia, University of Brescia, Italy )
Jordann Lewis
( clinical research coordinator, left to attend medical school)
Cesia Rosamilia
( clinical research coordinator, left to attend physician assistant school)
Arielle Coughlin
( clinical research coordinator, left to attend medical school)
Rachel Reingold
( clinical research coordinator, left to attend medical school)
Lucrezia Carlassara, MD
(Nephrologist at AULSS1)
Natalia DeMaria
(lab technician, currently Research Support Specialist at SUNY Upstate Medical Hospital)
Emily Groopman, PhD
(returned to Medical School)
Priya Krithivasan
Bioinformatician (Left to work as bioinformatics scientist at Covance in Redmond, WA)
Katelyn Burgess
Instructor of Pediatrics, At Northwestern University Feinberg School of Medicine
Yasar Caliskan, MD
Transplant Nephrologist at Saint Louis University School of Medicine
Travis CreveCoeur
Lab tech (Resident, Columbia, Neurosurgery)
David Fasel
Director of Bioinformatics at CPMG
Clara Fischman
Lab tech (Resident in Internal Medicine, Penn Medicine)
Krzysztof Kiryluk, MD, MS
Associate Professor of Medicine at CUMC and now heads the Kiryluk Lab.
Francesca Lugani, MD, PhD
Returned to Pediatric Nephrology, Gianni Gaslini Institute, Italy
Jason McCutchan
Lab tech (left to work as a software developer at TD Securities.)
Shannon Nees, MD
Took job as a House Officer in Pediatrics, Morgan Stanley Children Hospital at Columbia University
Ami Patel
Lab manager (left to attend medical school)
Brittany Perry
Lab tech (left to attend medical school)
Sindhuri Prakash-Polet, M.D/Ph.D
MD/PhD student (Renal fellow at CUIMC)
Mersedeh Rohanizadegan, MD
clinical geneticist in Boston, Massachusetts
Simone Sanna-Cherchi, MD
Associate Professor at Columbia University Irving Medical Center and now heads the Sanna-Cherchi lab
Samantha Shapiro, MD
Medical Student (left to complete residency at Mt. Sinai Hospital)
Meghan Sise, MD
Research Fellow (took job as a Research Fellow at Massachusetts General Hospital)
Roel Sterken, PhD
Left to become Project Development Manager at DROiA, Belgium
Rosemary Thomas, MD
Associate Professor, Children’s National, Washington, DC
Katarina Vukojevic MD, PhD, MSc
Postdoctoral Fellow (left to head the Department of Anatomy, Histology and Embryology and Laboratory for Early Human Development at the University of Split Croatia, School of Medicine,Associate Professor)
Patty Weng, MD
currently Assistant Clinical Professor of Pediatrics – Nephrology, Medical Director, Pediatric Kidney Transplant Program, UCLA
Rik Westland, MD, PhD
Post-Doctoral Fellow (pediatric nephrology fellow at Amsterdam UM)
Others:
Elena Sanchez-Rodriguez, PhD Youngji Na, PhD; Sergey Kisselev; Wan Yee Lam; Nicola Mongera, MD; Sheena Kapoor; Shreya Sirivolu; Javier De Andre Cattle Kelvin Chan; Michael DiVecchia, LPN; Feyan Dong, MD; Nilgun Kacak, MD; Hussein Karnib, MD; Anita Konka, MD; Sneh Lata; Yifu Li, MD; Esther Lopez-Rivera, PhD; Riccardo Magistroni, MD; Jeremiah Martino, PhD; Natalia Papeta, PhD; Adam Reese, MD; Holly Snyder; Jingyuan Xie, MD; Shouhong Xuan, PhD
