The Lab’s main focus is to identify genetic causes of clinically-relevant kidney disease occurring across the lifespan of the individual and to translate these findings into mechanisms and potential treatments.

We study congenital anomalies of the kidney and urinary tract (CAKUT) and idiopathic nephrotic syndrome (INS) caused by minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) using large-scale human genetic approaches and functional modeling in mice.